The Art and Science of Selecting a CD123-Specific Chimeric Antigen Receptor for Clinical Testing
نویسندگان
چکیده
منابع مشابه
CD123 AML targeting by chimeric antigen receptors
Chimeric antigen receptor (CAR) modified T cells have emerged as powerful tools for controlling leukemias. We recently showed that anti-CD123 CAR-expressing cytokine-induced killer T cell treatment is an effective immunotherapeutic approach to eradicate Acute Myeloid Leukemia (AML) cells. Here, we discuss how this genetically modified cell-based strategy could be relevant to the field of AML th...
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ژورنال
عنوان ژورنال: Molecular Therapy - Methods & Clinical Development
سال: 2020
ISSN: 2329-0501
DOI: 10.1016/j.omtm.2020.06.024